Drug (API) Microencapsulation Systems- Universal Analytical Technology China

产品信息

Drug (API) Microencapsulation Systems

Encapsulate APIs in PLGA particles

Brand：Dolomite

Description Specifications

Microfluidic technology & benefits

Microfluidics, or “lab-on-a-chip” technology, provides precise control and manipulation of fluids in the micro to picolitre range and can be used to manipulate living matter.

Dolomite is pioneering the use of microfluidic devices for small-scale fluid control and analysis, enabling engineers and scientists to take full advantage of the following :

	Traditional methods (batch)	Microfluidic methods
API Encapsulation efficiency	up to 30%	up to 99 %

Coefficient of variation (CV)	up to 20%	up to 1%

Particle size distribution	Broad	Narrow

Particle monodispersity	Poor	Narrow

Waste	~50%	Near 0%

Reproducibility	Low	High

Particle size control	Poor	Precise

System specifications

Droplet size	Particle size from 50 nm to 50 µm in diameter (depending on system version)
Droplet monodispersity	Extremely monodisperse, CV < up to 1%.
Droplet generation frequency	Up to 10 kHz for a standard system and up to a MHz for a Telos® production system (depending on reagents and droplet sizes).
Flow rate range	From 70 nL/min to 5 mL/min, depending on pressure, viscosity and channel geometry (flow resistance).
Flow pressure	Flexible with vacuum and pressure capability in the same pump (pump pressure range: 0-10 bar). Pumps contain integrated reservoir to eliminate the risk of vial fracture in operation.
Chemical resistance	Very high (wetted materials: glass, PEEK, ETFE, FEP, PTFE).

Related recommendations

Single Emulsion Systems
Brand：Dolomite

Double Emulsion Systems
Brand：Dolomite

Educational Microfluidic Systems
Brand：Dolomite